Compare Peptides

Select any two compounds for a side-by-side comparison of mechanism, uses, risks, and FDA regulatory status.

Popular comparisons

Tirzepatide

Mounjaro, Zepbound

FDA Approved
GLP-1/GIP Dual Agonist

AOD-9604

Anti-Obesity Drug 9604, Tyr-hGH Fragment 177-191

Category 1
Metabolic
Overview

A dual GIP and GLP-1 receptor agonist developed by Eli Lilly. Represents the next generation of incretin-based therapies with potentially superior efficacy to semaglutide for weight loss.

A modified fragment of human growth hormone (amino acids 177-191) originally developed as an anti-obesity agent. Targets fat metabolism without the growth-promoting effects of full HGH.

Mechanism of Action

Activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors, producing enhanced insulin secretion, appetite suppression, and metabolic improvements beyond what single-agonist drugs achieve.

Stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat formation) by mimicking the fat-reducing action of natural growth hormone without affecting blood sugar or tissue growth.

Common Uses
  • Weight management
  • Type 2 diabetes treatment
  • Metabolic health improvement
  • Fat loss
  • Metabolic health
  • Body composition improvement
  • Cartilage repair (emerging research)
Known Risks
  • GI side effects (nausea, diarrhea, vomiting)
  • Pancreatitis risk
  • Injection site reactions
  • Potential thyroid concerns
  • Limited efficacy data in humans
  • Injection site reactions
  • Headaches
  • Phase 2 trials showed modest results
Regulatory Status
FDA Approved

FDA-approved as Mounjaro (diabetes, 2022) and Zepbound (weight management, 2023).

Category 1

Reclassified to Category 1 in February 2026 as part of the HHS announcement restoring compounding access. Not affected by the April 15, 2026 Category 2 removal action. Previously reached Phase 2 clinical trials for obesity but was not pursued further by the original developer. Available through licensed 503A compounding pharmacies with a physician prescription.

This comparison is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any peptide therapy.