REGULATORY EVENT

PCAC Meeting Tracker — July 23–24, 2026

The FDA's Pharmacy Compounding Advisory Committee will evaluate 7 peptides for potential addition to the 503A bulk drug substances list. Track each compound's progress and sign up for same-day email alerts.

Day 1 — July 23, 2026

BPC-157

Healing & Recovery

Day 1
Gut healingTendon repairAnti-inflammatory
Regulatory Progress1/4 stages
Cat 2 RemovalPublic CommentPCAC ReviewFDA Decision
KPV

Anti-Inflammatory

Day 1
Gut inflammationIBD supportImmune modulation
Regulatory Progress1/4 stages
Cat 2 RemovalPublic CommentPCAC ReviewFDA Decision
MOTS-c

Metabolic

Day 1
Metabolic regulationExercise mimeticInsulin sensitivity
Regulatory Progress1/4 stages
Cat 2 RemovalPublic CommentPCAC ReviewFDA Decision
TB-500

Healing & Recovery

Day 1
Wound healingTissue repairAnti-fibrotic
Regulatory Progress1/4 stages
Cat 2 RemovalPublic CommentPCAC ReviewFDA Decision

Day 2 — July 24, 2026

Emideltide (DSIP)

Sleep & Recovery

Day 2
Sleep regulationStress reductionOpioid withdrawal
Regulatory Progress1/4 stages
Cat 2 RemovalPublic CommentPCAC ReviewFDA Decision
Epitalon

Anti-Aging & Longevity

Day 2
Telomerase activationCircadian regulationAnti-aging
Regulatory Progress1/4 stages
Cat 2 RemovalPublic CommentPCAC ReviewFDA Decision
Semax

Nootropic & Cognitive

Day 2
BDNF upregulationNeuroprotectionCognitive enhancement
Regulatory Progress1/4 stages
Cat 2 RemovalPublic CommentPCAC ReviewFDA Decision

Group 2 — By February 2027

5 additional compounds will be reviewed at a second PCAC meeting: GHK-Cu, Melanotan II, LL-37 (Cathelicidin), Dihexa, and PEG-MGF. Exact date TBD.

What to Expect

Before the Meeting

  • FDA publishes briefing documents (~2 weeks before)
  • Public comment period closes July 9
  • Oral presentation requests due June 30
  • Committee member list published

During the Meeting

  • FDA presents safety/efficacy data per compound
  • Public oral presentations (if approved)
  • Committee discussion and questions
  • Advisory vote per compound (recommend or not)

After the Meeting

  • PCAC recommendation is advisory (not binding)
  • FDA decides whether to accept the recommendation
  • If accepted, formal rulemaking to add to 503A list
  • Timeline from vote to final rule: weeks to months

Important Context

  • A favorable vote ≠ immediate compounding authorization
  • The prior PCAC panel voted to keep restrictions
  • New committee composition may change the outcome
  • Read our legal analysis

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