Thymalin
UnregulatedAlso known as: Thymic peptide extract, Thymus extract
Immune & LongevityLast reviewed: April 28, 2026
A thymic peptide bioregulator developed by Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. Thymalin is a complex of polypeptides extracted from the thymus gland that has been used clinically in Russia since the 1980s for immune restoration. Khavinson's research group reported that thymalin treatment in elderly patients was associated with reduced mortality over a 6-year follow-up period.
Mechanism of Action
Contains a mixture of thymic peptides that restore T-cell function and thymic output. Proposed to act through epigenetic mechanisms, reactivating genes involved in immune function that become silenced with aging. May promote thymic regeneration and restore the balance between T-helper and T-suppressor cells.
Common Uses
- Immune system restoration in elderly patients
- Post-infection immune recovery
- Anti-aging and longevity protocols
- Adjunct to cancer immunotherapy (in Russian clinical practice)
Known Risks
- Limited Western clinical data
- Most research from Russian institutions — peer review concerns
- Allergic reactions possible (animal-derived extract)
- Quality varies significantly between sources
Regulatory Status
Not FDA-approved or recognized. Used clinically in Russia and some CIS countries. No FDA category. Available only as a research peptide in the US. Khavinson's longevity claims, while published, have not been replicated in Western clinical trials.
Common Protocols
Protocol information is for educational reference only. Dosing varies significantly by individual, condition, and physician guidance. Always work with a licensed healthcare provider.
Intramuscular injection
Typical Dose
10 mg
Frequency
Daily for 5–10 days
Cycle Length
1–2 courses per year
Khavinson protocol: 10 mg IM daily for 5–10 days, repeated 1–2 times per year. Often combined with epithalon in Russian longevity protocols. The short course duration is characteristic of bioregulator peptide therapy.
Related Compounds
Research References
This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any peptide therapy. Data is compiled from published research and regulatory sources and may not reflect the most recent developments.