Compare Peptides
Select any two compounds for a side-by-side comparison of mechanism, uses, risks, and FDA regulatory status.
Popular comparisons
A tripeptide (glutamate-cysteine-glycine) that is the body's most abundant endogenous antioxidant. Plays a critical role in detoxification, immune function, and cellular protection. Available in oral, IV, and injectable forms.
A 21-amino acid peptide encoded within the mitochondrial genome — one of the first mitochondria-derived peptides (MDPs) discovered. Humanin levels decline with age and are associated with longevity in centenarian offspring. Studied for neuroprotection, metabolic health, and cardiovascular protection.
Neutralizes reactive oxygen species (ROS) and free radicals. Conjugates toxins for excretion via the liver (Phase II detoxification). Regenerates other antioxidants (vitamins C and E). Supports T-cell function and immune regulation.
Binds to multiple receptors including gp130, FPRL1, and intracellular IGFBP-3. Activates STAT3 and AMPK signaling pathways. Inhibits neuronal apoptosis, reduces inflammation, improves insulin sensitivity, and protects against ischemic injury. Acts as a stress-response signal from mitochondria to the rest of the cell.
- Antioxidant support
- Liver detoxification
- Skin brightening
- Immune support
- Heavy metal chelation support
- Anti-aging
- Neuroprotection and cognitive support
- Metabolic health and insulin sensitivity
- Cardiovascular protection
- Longevity and anti-aging protocols
- Alzheimer's disease research
- Oral bioavailability is poor (liposomal forms better)
- IV glutathione generally well-tolerated
- Rare allergic reactions
- Skin lightening effect is controversial
- May interfere with chemotherapy drugs
- Very limited human clinical data
- Optimal dosing not established
- Long-term effects unknown
- Injection site reactions
- Interactions with other peptides not well characterized
Available as a dietary supplement (oral) and through IV clinics. Not FDA-approved for any medical indication. No regulatory restrictions on supplement form.
Not FDA-approved and not on any compounding list. Available as a research chemical. One of the more scientifically interesting longevity peptides with a growing research base, but human clinical trials are in early stages. Not affected by the 2026 regulatory changes.
This comparison is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any peptide therapy.