Compare Peptides
Select any two compounds for a side-by-side comparison of mechanism, uses, risks, and FDA regulatory status.
Popular comparisons
A tripeptide (glutamate-cysteine-glycine) that is the body's most abundant endogenous antioxidant. Plays a critical role in detoxification, immune function, and cellular protection. Available in oral, IV, and injectable forms.
A coenzyme found in all living cells that plays a central role in energy metabolism and cellular repair. NAD+ levels decline significantly with age. Injectable NAD+ and its precursors (NMN, NR) have become widely used in longevity and anti-aging protocols.
Neutralizes reactive oxygen species (ROS) and free radicals. Conjugates toxins for excretion via the liver (Phase II detoxification). Regenerates other antioxidants (vitamins C and E). Supports T-cell function and immune regulation.
Serves as an electron carrier in cellular respiration (ATP production). Activates sirtuins (SIRT1-7), a family of proteins involved in DNA repair, inflammation regulation, and metabolic homeostasis. Also activates PARP enzymes involved in DNA damage repair.
- Antioxidant support
- Liver detoxification
- Skin brightening
- Immune support
- Heavy metal chelation support
- Anti-aging
- Anti-aging and longevity protocols
- Energy and cognitive enhancement
- Addiction recovery support
- Athletic performance and recovery
- Metabolic health optimization
- Oral bioavailability is poor (liposomal forms better)
- IV glutathione generally well-tolerated
- Rare allergic reactions
- Skin lightening effect is controversial
- May interfere with chemotherapy drugs
- IV infusions can cause flushing, nausea, chest tightness (usually transient)
- Oral precursors (NMN, NR) generally well-tolerated
- Long-term effects of supraphysiological dosing unknown
- Theoretical concern: NAD+ may support cancer cell metabolism
- Quality varies significantly across suppliers
Available as a dietary supplement (oral) and through IV clinics. Not FDA-approved for any medical indication. No regulatory restrictions on supplement form.
NAD+ itself is not FDA-approved as a drug. Injectable NAD+ is available through compounding pharmacies with a prescription. Oral precursors (NMN, NR) are sold as dietary supplements. Not on any FDA compounding category list — exists in a separate regulatory framework from the peptides affected by the 2026 reclassification.
This comparison is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any peptide therapy.