AHK-Cu
UnregulatedAlso known as: Copper Tripeptide AHK, Ala-His-Lys:Copper
Anti-Aging & SkinLast reviewed: April 28, 2026
A newer copper-binding tripeptide related to GHK-Cu but with a different amino acid sequence (Ala-His-Lys vs Gly-His-Lys). Emerging research suggests it may have distinct and potentially complementary effects on hair growth and skin rejuvenation.
Mechanism of Action
Binds copper ions similarly to GHK-Cu but activates different signaling pathways. Appears to stimulate Wnt/β-catenin signaling in hair follicle dermal papilla cells, promoting hair growth through a mechanism distinct from GHK-Cu's wound healing pathway.
Common Uses
- Hair growth stimulation
- Skin rejuvenation
- Anti-aging
- Wound healing support
Known Risks
- Very limited research compared to GHK-Cu
- Most studies are in vitro
- Potential copper toxicity at high doses
- Not well-characterized safety profile
Regulatory Status
No FDA regulatory category. Available as a research chemical and in some cosmetic formulations. Not subject to the same regulatory scrutiny as GHK-Cu injectable.
Common Protocols
Protocol information is for educational reference only. Dosing varies significantly by individual, condition, and physician guidance. Always work with a licensed healthcare provider.
Topical (serum/solution)
Typical Dose
0.01–0.1% concentration
Frequency
Once or twice daily
Cycle Length
Ongoing
Primarily used topically for hair and skin. Less research than GHK-Cu. Often combined with GHK-Cu in formulations for complementary effects.
Related Compounds
Research References
This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any peptide therapy. Data is compiled from published research and regulatory sources and may not reflect the most recent developments.