Hormonal & Reproductive
3 compounds in this category.
Kisspeptin
InvestigationalKisspeptin-54, Kisspeptin-10
A neuropeptide that acts as the master regulator of the reproductive hormone axis. Kisspeptin neurons in the hypothalamu…
Route
Subcutaneous or intravenous injection
Dose
1.0–6.4 nmol/kg (kisspeptin-54) or 0.3–1.0 nmol/kg (kisspeptin-10)
Cycle
Single administration or short course
Fertility treatment (investigational)Hypogonadism evaluationIVF protocols (as GnRH trigger alternative)
Gonadorelin
FDA ApprovedGnRH, Gonadotropin-Releasing Hormone
A synthetic form of the naturally occurring gonadotropin-releasing hormone (GnRH). Used clinically to evaluate pituitary…
Route
SubQ
Dose
100–200 mcg
Cycle
Ongoing (concurrent with TRT)
Maintaining fertility during TRTPituitary function testingHypothalamic amenorrhea treatment
Enclomiphene
InvestigationalAndroxal, trans-Clomiphene
The trans-isomer of clomiphene citrate, a selective estrogen receptor modulator (SERM). Unlike the mixed isomer clomifen…
Route
Oral
Dose
12.5–25 mg
Cycle
Ongoing or 8–12 week cycles
Secondary hypogonadism treatmentTestosterone optimization without TRTPost-cycle therapy (PCT)
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